In 2004, Guinoo joined the popular reality search Star Circle Teen Quest via ABS-CBN and made it to the Top 5 finalist or much known as the "Magic Circle of 5", along with co-questors Hero Angeles, Sandara Park, Joross Gamboa, and Melissa Ricks. On June 2004, the Grand Questor's Night was held in Araneta Coliseum, and she won 2nd Runner up. She was launched as one of the newest member of ABS-CBN's Star Magic. She was also paired, as a love team, with Joross Gamboa, even before Star Circle Quest ended. Her first show with ABS-CBN was with the youth oriented drama SCQ Reload, with co-former SCQ finalists.
She also played in movies like Now That I Have You , Can This Be Love, and D' Anothers.
Her biggest break came when she was one of the lead casts of the drama series Sineserye Presents: Natutulog Ba Ang Diyos?, with big stars like Dina Bonnevie and Rosanna Roces. In 2008, she started her first-ever solo teleserye in ABS-CBN entitled Ligaw na Bulaklak which airs in an afternoon slot. Presently she is one of mainstay of comedy show entitle Everybody Hapi over TV5 as Jenny with John Estrada, Eugene Domingo, Long Mejia, Alex Gonzaga and Matt Evans.
